INTERNATIONAL CONSENSUS VALIDATION OF THE POPI TOOL (PEDIATRICS: OMISSION OF PRESCRIPTIONS AND INAPPROPRIATE PRESCRIPTIONS) TO IDENTIFY INAPPROPRIATE PRESCRIBING IN PEDIATRICS.

International consensus validation of the POPI tool (Pediatrics: Omission of Prescriptions and Inappropriate prescriptions) to identify inappropriate prescribing in pediatrics.

IntroductionWhile drug prescription should be based on established recommendations stemming from clinical trials but in pediatrics, many drugs are used without marketing authorization.Consequently recommendations are often based on clinical experience and the risk of inappropriate prescription (IP) is high.A tool for detecting IP in pediatrics-call

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Protocol of a scoping review of outcome domains in dermatology

Introduction Core outcome sets (COSs) are agreed outcomes (domains (subdomains) and instruments) that should be measured as a minimum in clinical trials or practice in certain diseases or clinical fields.Worldwide, the number of COSs is increasing and there might be conceptual overlaps of domains (subdomains) and instruments within disciplines.The

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QL1604 combined with bevacizumab as an innovative first-line treatment for HCC patient with extensive metastasis who showed remarkable effect: a case report

Hepatocellular carcinoma (HCC) majicontrast red is a common and highly malignant tumor with poor outcomes, especially when it metastasizes.In this report, we present the case of a 64-year-old male patient diagnosed with recurrence and multiple metastases of HCC 7 years after surgery.As the tumor invaded the spinal canal and pressed on the spinal co

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Whole blood and blood components from vertebrates differentially affect egg formation in three species of anautogenous mosquitoes

Abstract Background Most female mosquitoes are anautogenous paintable magnets and must blood feed on a vertebrate host to produce eggs.Prior studies show that the number of eggs females lay per clutch correlates with the volume of blood ingested and that protein is the most important macronutrient for egg formation.In contrast, how whole blood, blo

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